RAF Typhoon FGR4s have joined forces with French warplanes in a coordinated attack against an underground arms cache in Syrian territory used by the IS group, according to the British defence ministry.
The facility, located using intelligence, was thought to be storing arms and explosives, the statement said, and was situated in mountainous terrain just above the ancient city of Palmyra in central Syria.
"Our aircraft utilized laser-guided Paveway IV weapons to target a number of access tunnels providing entry to the site... early reports suggest the objective was successfully hit," officials stated.
There was no sign of any harm to civilians in the strike conducted Saturday night and each participating jet returned safely, the MoD added.
The British jets were supported by a Voyager aerial refuelling aircraft.
Daesh - referred to as the so-called Islamic State - enforced jihadist rule over large swathes of Syria and Iraq until 2019.
"This action shows British leadership, and commitment to work closely with allied nations, to eliminate any revival of IS and their harmful and extremist ideologies in the area," UK Defence Secretary John Healey stated.
British military aircraft have conducted patrols over Syrian airspace to "forestall any attempted comeback" of Islamic State subsequent to its routing at the battle of Baghuz in the year 2019, the ministry said.
"I must thank the personnel of British forces who took part in this strike for their professionalism and their bravery," he said. "Including them were thousands of British personnel on duty over the festive period. This action, to eliminate militants who pose a risk to our safety, demonstrates how UK forces are always on standby, continuously, ensuring Britain's security at home and strong abroad."
In December, the United States armed forces carried out what it described as a "major assault" on IS targets in Syria, after an assault killed two American soldiers and a civilian linguist in Palmyra.
The U.N. estimates Daesh still maintains between 5,000 and 7,000 fighters in Iraq and Syria.
